Exogenous bone morphogenetic protein-7 reduces hepatic fibrosis in<i>Schistosoma japonicum</i>-infected mice<i>via</i>transforming growth factor-β/Smad signaling

Abstract

Exogenous BMP-7 significantly decreased the degree of hepatic fibrosis in both the acute and chronic stages of hepato-schistosomiasis, and the regulatory mechanism may involve the TGF-β/Smad signaling pathway.