Further delineation of the phenotype of chromosome 14q13 deletions: (positional) involvement of <i>FOXG1</i> appears the main determinant of phenotype severity, with no evidence for a holoprosencephaly locus

Abstract

FOXG1 appears the main determinant of the severity of phenotypes resulting from deletions including 14q13. The collected data show no evidence for a locus for holoprosencephaly in the 14q13 region, but a locus for agenesis of the corpus callosum cannot be excluded.