Epizootic of toxoplasmosis in kangaroos, wallabies, and potaroos: Possible transmission via domestic cats

Abstract

ceptible species, but usually include depression, fever, excessive salivation, tremors, and convul sions. 1 --< Although the bear of the present report was staggering and shaking, the clinical signs ofpseudo rabies may have been masked by clinical signs caused by the volvulus.Macroscopic lesions of pseudorabies in swine and other species include evidence of self trauma, con gested meninges, pulmonary edema, and 1-to 2-mm foci of necrosis in the liver, spleen, kidneys, tonsils, or lymph nodes. 1 --< Occasionally, herpetic vesicles de velop on the snout of affected pigs. 1 Histologic lesions of pseudorabies include multi focal to diffuse nonsuppurative meningoencephalitis and ganglioneuritis. 1 -2 Usually, lesions are the most severe in the rostral portion of the cerebrum.Intra nuclear glial inclusion bodies are not found easily in infected animals.Other histologic lesions include diffuse pulmonary and hepatic congestion.Multi focal small areas of coagulative necrosis may be seen in the hepatic or splenic parenchyma and may be accompanied by intranuclear inclusion bodies. 1 -2The natural route of pseudorabies virus infection is inhalation or ingestion of the virus.The naso oropharynx is the site of viral replication.The virus migrates to the CNS via the cranial nerves or perineural lymphatics and is simultaneously re leased from the upper respiratory tract, causing an intermittent viremia.Pneumonia, splenitis, and hepatitis may develop.