Polymorphism of the 5′ flanking region of the IL-12 receptor β2 gene partially determines the clinical types of leprosy through impaired transcriptional activity - Concepedia

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Polymorphism of the 5′ flanking region of the IL-12 receptor β2 gene partially determines the clinical types of leprosy through impaired transcriptional activity

DOI Full Paper Access

33

Citations

22

References

2005

Year

Hideki Ohyama, Koretsugu Ogata, Kazu Takeuchi, Masako Namisato, Yuma Fukutomi, Fusanori Nishimura, H Naruishi, Tetsuya Ohira, Kumiko Hashimoto, Tao Liu,

Journal of Clinical Pathology

Abstract

SNPs within the 5' flanking region of IL12RB2 affect the degree of expression of this gene and may be implicated in individual differences in CMI responsiveness to mycobacterial antigens, leading to lepromatous or tuberculoid leprosy.

References

	Year	Citations

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