Histopathological findings of failed grafts following Descemet’s stripping automated endothelial keratoplasty (DSAEK)

Abstract

Irregular or thick graft, graft-host interface fibrous/epithelial ingrowth, and infection all predispose to DSAEK failures related to graft detachment. Endothelial cells attenuation and retrocorneal fibrous membrane are major causes for primary graft failure.