A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.6K citations

Life Sciences, Biochemistry, Bioinformatics +9

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

Berk Hess, Carsten Kutzner, David van der Spoel et al. · Journal of Chemical Theory and Computation · 2008 · 16K citations · Full text

Natural Sciences, Chemistry, High-performance Computing +17

X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Raimund Dutzler, Ernest B. Campbell, Martine Cadène et al. · Nature · 2002 · 1.6K citations

Natural Sciences, Biochemistry, Chemistry +17

Evaluation of comparative protein modeling by M<scp>ODELLER</scp>

Andrej Šali, Liz Potterton, Yuan Feng et al. · Proteins Structure Function and Bioinformatics · 1995 · 1.1K citations

Life Sciences, Biochemistry, Biophysics +13

Spectrum of mutations in the major human skeletal muscle chloride channel gene (CLCN1) leading to myotonia.

Christof Meyer-Kleine, Klaus Steinmeyer, K. Ricker et al. · PubMed · 1995 · 165 citations

Life Sciences, Genetics, Molecular Genetics +10