H<sub>2</sub>O<sub>2</sub>-Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup>Channel Activation - Concepedia

Concepedia

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H<sub>2</sub>O<sub>2</sub>-Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup>Channel Activation

DOI Full Paper Access

160

Citations

29

References

2011

Year

David X. Zhang, Léna Borbouse, Debebe Gebremedhin, Suelhem A. Mendoza, Natalya S. Zinkevich, Rongshan Li, David D. Gutterman

Circulation Research

Abstract

H(2)O(2) dilates HCAs through a novel mechanism involving protein dimerization and activation of PKG-Iα and subsequent opening of smooth muscle BK(Ca) channels.

References

	Year	Citations

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