Arthritis & Rheumatism · 1985 · 238 citations · 5 references
DentistryImmunologyAllergyHypersensitivitySalivary DiagnosticsOral Disease DiagnosticsSalivary DisordersSalivary GlandsDiagnosis Of XerostomiaXerostomia Screening ToolsXerostomia Severity Assessment
The study introduces a simple, low‑cost xerostomia test using a folded sterile sponge chewed for 2 minutes. Saliva output is measured by weighing the sponge before and after chewing. Normal controls produced ≤2.75 g of saliva in 2 min, whereas 3/32 allergy–immunology and 9/38 rheumatology outpatients had significantly reduced output, and sicca symptoms correlated with abnormal tear and saliva production.
Abstract We describe a simple, reproducible, and low‐cost test for xerostomia, which involves chewing on a folded sterile sponge for 2 minutes. Saliva production is quantitated by weighing the sponge before and after chewing. Normal control subjects produced ≤ 2.75 gm of saliva in 2 minutes. Three of 32 consecutive, unselected outpatients in allergy–immunology clinics and 9 of 38 patients in rheumatology clinics had decreased saliva production, which was significantly different compared with controls ( P < 0.01). The presence of sicca symptoms was highly correlated with quantitatively abnormal tear and saliva production, according to the results of the Saxon and Schirmer's tests.
5
Tests for Linear Trends in Proportions and Frequencies
P. Armitage · Biometrics · 1955 · 2.1K citations
The oral component of Sjögren's syndrome
T. E. Daniels, S Silverman, J. Michalski et al. · Oral Surgery Oral Medicine Oral Pathology · 1975 · 203 citations
Sjogren's syndrome. I. Sicca components.
K Whaley, John Williamson, Chisholm Dm et al. · PubMed · 1973 · 110 citations
Sjøgren's Syndrome<subtitle>I. SICCA COMPONENTS</subtitle>
K Whaley, John Williamson, D. M. Chisholm et al. · QJM · 1973 · 31 citations