Specificity of Watson–Crick Base Pairing on a Solid Surface Studied at the Atomic Scale

Abstract

Surface Watson–Crick base pairing makes binary mixtures of the complementary nucleobases guanine (G) and cytosine (C) on Au(111) thermally stable up to the desorption temperature of the bases, whereas binary mixtures of the noncomplementary adenine (A) and cytosine segregate on heating (see STM images with DFT structures). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.