A Short Route to α‐Tocopherol

Abstract

Short and sweet: A simple and practical route to α-tocopherol is described (see scheme; TES=triethylsilyl). The key step is a remarkably diastereoselective domino aldol/oxa-Michael reaction, which is promoted by proline derivative 1. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z801765_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.