Angiotensin II Inhibits Endothelial Cell Motility Through an AT<sub>1</sub>-Dependent Oxidant-Sensitive Decrement of Nitric Oxide Availability - Concepedia

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Angiotensin II Inhibits Endothelial Cell Motility Through an AT<sub>1</sub>-Dependent Oxidant-Sensitive Decrement of Nitric Oxide Availability

52

Citations

23

References

2003

Year

Giovambattista Desideri, Maria Cristina Bravi, Marzia Tucci, Giuseppe Croce, Maria Contina Marinucci, Anna Santucci, Edoardo Alesse, Claudio Ferri

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

All together, our data demonstrate that angiotensin II inhibits HUVEC motility by reducing NO availability. Such reduction is due to an angiotensin II type 1 receptor-dependent increment in intracellular ROS generation.

References

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