Efficient Gold(I)‐Catalyzed Direct Intramolecular Hydroalkylation of Unactivated Alkenes with α‐Ketones

Abstract

Easy access by gold: The AuI-catalyzed title reaction provides simple and efficient access to highly substituted cyclic compounds with excellent yields and good diastereoselectivity. This transformation constitutes the first example of transition-metal-catalyzed direct hydroalkylation of unactivated alkenes with simple α-ketone groups in the absence of additive reagents. Bn=benzyl, Ts=tosyl.