Effect of diazepam on cortical 5-HT release and behaviour in the guinea-pig on exposure to the elevated plus maze

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

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The use of a plus-maze to measure anxiety in the mouse

Richard G. Lister · Psychopharmacology · 1987 · 2.6K citations

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An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat

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Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

Sharon Pellow, Sandra E. File · Pharmacology Biochemistry and Behavior · 1986 · 1.5K citations

Medicine, Neuroscience, Pharmacology +13

5-HT and mechanisms of defence

J.F.W. Deakin, Frederico Guilherme Graeff · Journal of Psychopharmacology · 1991 · 1K citations

Life Sciences, Pharmacology, Physiology +10