Concepedia

Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia–reperfusion injury in rat hearts

P DINAPOLI, Alfonso Antonio Taccardi, Alfredo Grilli, M.A. Delutiis, A Barsotti, Mario Felaco, R. DeCaterina

Cardiovascular Research · 2005 · 112 citations · 47 references

DOI

Abstract

Chronic treatment with rosuvastatin before ischemia reduces ischemia-reperfusion injury and prevents coronary endothelial cell and cardiomyocyte damage by NO-dependent mechanisms.

References

47

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

Anders Olsson, John J.V. McMurray, G Thorgeirsson et al. · The Lancet · 1994 · 8.5K citations

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The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

Frank M. Sacks, Marc A. Pfeffer, Lemuel A. Moyé et al. · New England Journal of Medicine · 1996 · 7.5K citations · Full text

Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

James Shepherd, Stuart M. Cobbe, Ian Ford et al. · New England Journal of Medicine · 1995 · 7.5K citations · Full text

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

The Lancet · 2002 · 7K citations

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Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

New England Journal of Medicine · 1998 · 5.3K citations · Full text