The use of a continuous flow-reactor employing a mixed hydrogen–liquid flow stream for the efficient reduction of imines to amines

Steen Saaby, Kristian Rahbek Knudsen, Mark Ladlow, Steven V. Ley

Chemical Communications · 2005 · 123 citations · 17 references

Concepts

Abstract

Imines have been reduced to amines in high yield, and with excellent chemoselectivity, by catalytic hydrogenation in a continuous flow-reactor, utilising an electrochemically-generated hydrogen source to produce a mixed hydrogen-liquid flow stream.

References

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