Concepedia

Effects of the long‐term administration of alendronate on the mechanical properties of the basal bone and on osseointegration

Mário Henrique Arruda Verzola, Fausto Frizzera, Guilherme José Pimentel Lopes de Oliveira, Rosa Maria Rodrigues Pereira, Ubirajara Pereira Rodrigues Filho, Keico Okino Nonaka, Silvana Regina Perez Orrico

Clinical Oral Implants Research · 2014 · 19 citations · 34 references

DOI

Abstract

Previous long-term therapy with alendronate caused an increase in the BMD, maximal force of fracture of the bone without changing the inorganic composition and elastic deformability of this tissue. Furthermore, the ALD therapy enhanced osseointegration.

References

34

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Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women

Georges Boivin, Pascale Chavassieux, Arthur C. Santora et al. · Bone · 2000 · 575 citations

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The bisphosphonate alendronate (MK-217) inhibits bone loss due to ovariectomy in rats

J.G. Seedor, H. Quartuccio, David D. Thompson · Journal of Bone and Mineral Research · 1991 · 396 citations · Full text

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Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women

Paul Roschger, S Rinnerthaler, John Yates et al. · Bone · 2001 · 385 citations

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