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A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist

Drug TargetBiochemistryFunctional SelectivityMedicineG Protein-coupled ReceptorReceptor (Biochemistry)NeuropharmacologyPharmacotherapyNon-peptide LigandPharmacologyDrug Discovery