Concepedia

Design, synthesis, and bioevaluation of benzamides: Novel acetylcholinesterase inhibitors with multi-functions on butylcholinesterase, Aβ aggregation, and β-secretase

Da‐Yong Peng, Qi Sun, Xiao‐Lei Zhu, Hong‐Yan Lin, Qiong Chen, Ningxi Yu, Wen‐Chao Yang, Guang‐Fu Yang

Bioorganic & Medicinal Chemistry · 2012 · 43 citations · 38 references

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References

38

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

, , +17

Thioflavine T interaction with synthetic Alzheimer's disease <i>β</i>‐amyloid peptides: Detection of amyloid aggregation in solution

Harry LeVine · Protein Science · 1993 · 2.2K citations · Full text

, , +16

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

Michal Harel, Isabelle J. Schalk, Laurence Ehret‐Sabatier et al. · Proceedings of the National Academy of Sciences · 1993 · 903 citations

, , +16

Acetylcholinesterase: From 3D structure to function

Hay Dvir, Israel Silman, Michal Harel et al. · Chemico-Biological Interactions · 2010 · 778 citations

, , +10