“On water” synthesis of N-unsubstituted pyrazoles: semicarbazide hydrochloride as an alternative to hydrazine for preparation of pyrazole-3-carboxylate derivatives and 3,5-disubstituted pyrazoles

Abstract

A method for the conversion of 4-substituted-2,4-diketoester and 1-aryl-1,3-diketones into pyrazole compounds under “on water” conditions has been developed.