PROTEINURIA, GLOMERULOMEGALY AND FOCAL GLOMERULOSCLEROSIS IN A GROSSLY OBESE MAN WITH OBSTRUCTIVE SLEEP APNEA SYNDROME

Abstract

A grossly obese (149 kg) man with the sleep apnea syndrome was found to have proteinuria and a supernormal glomerular filtration rate. Renal histology showed glomerulomegaly and focal glomerulosclerosis. It is suggested that obesity may induce glomerular hyperfiltration and in turn glomerulosclerosis.