Circulation Arrhythmia and Electrophysiology · 2009 · 241 citations · 29 references
Loss of function mutations in sodium channel beta-subunits were identified in patients with AF and were associated with a distinctive ECG phenotype. These findings further support the hypothesis that decreased sodium current enhances AF susceptibility.
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Variants conferring risk of atrial fibrillation on chromosome 4q25
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<i>SCN5A</i> Mutation Associated With Dilated Cardiomyopathy, Conduction Disorder, and Arrhythmia
William P. McNair, Lisa Ku, Matthew R.G. Taylor et al. · Circulation · 2004 · 441 citations · Full text