The ultra-early protective effect of ulinastatin on rabbit acute lung injury induced by paraquat

Song Zu-jun, Gaofei Chen, Gang Lin, Chiyu Jia, Cao Jianxia, Guokun Ao

BMC Emergency Medicine · 2013 · 18 citations · 8 references

DOIFull text

Open access

Abstract

In the ultra-early stage of rabbit ALI induced by PQ, pulmonary vascular endothelial cell is damaged and serum VEGF mass concentration and pulmonary vascular permeability increase. Early ulinastatin intervention can reduce serum VEGF level and PQ-induced vascular permeability amplitude, indicating that ulinastatin has a protective effect on pulmonary vascular endothelial cells.

References

8