Microarray Analysis and Functional Characterization of the Nitrosative Stress Response in Nonmucoid and Mucoid <i>Pseudomonas aeruginosa</i>

Abstract

The type strain of Pseudomonas aeruginosa, PAO1, showed great upregulation of many nitrosative defense genes upon treatment with S-nitrosoglutathione, while the mucoid strain PAO578II showed no further upregulation above its constitutive upregulation of nor and fhp. NO* consumption however, showed that both strains mount functional, protein synthesis-dependent NO*-consumptive responses.