Concepedia

Relationship between ivabradine treatment and cardiovascular outcomes in patients with stable coronary artery disease and left ventricular systolic dysfunction with limiting angina: a subgroup analysis of the randomized, controlled BEAUTIFUL trial

Kim Fox, Ian Ford, Michał Tendera, Michele Robertson, Roberto Ferrari

European Heart Journal · 2009 · 218 citations · 33 references

DOI

Abstract

Our analyses raises the possibility that ivabradine may be helpful to reduce major cardiovascular events in patients with stable CAD and LVSD who present with limiting angina. However, a large-scale clinical trial is ongoing, which will formally test this hypothesis.

References

33

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)

The Lancet · 1999 · 5.1K citations

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The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial

The Lancet · 1999 · 4.9K citations

, , +9

Effect of Carvedilol on Survival in Severe Chronic Heart Failure

Milton Packer, Andrew J.S. Coats, Michael B. Fowler et al. · New England Journal of Medicine · 2001 · 3.1K citations · Full text

Effect of carvedilol on survival in severe chronic heart failure

Milton Packer, Andrew J.S. Coats, Michael B. Fowler · ACC Current Journal Review · 2001 · 1.7K citations

, , +5

Effect of Antihypertensive Agents on Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure

Steven E. Nissen, E. Murat Tuzcu, Peter Libby et al. · JAMA · 2004 · 1.1K citations