Electrospray ionization mass spectrometry of tributyltin(IV) complexes and their larvicidal activity on mosquito larvae: crystal and molecular structure of polymeric (Bu3Sn[O2CC6H4{NN(C6H3-4-OH(C(H)NC6H4OCH3-4))}-o])n

Abstract

A series of tributyltin(IV) complexes of 2-[(E)-2-(3-formyl-4-hydroxyphenyl)-1-diazenyl]benzoic acid and 4-[((E)-1-{2-hydroxy-5-[(E)-2-(2-carboxyphenyl)-1-diazenyl]phenyl}methylidene)amino]aryls have been investigated by electrospray mass spectrometry (ESI-MS) and tandem mass spectrometry (MSn) techniques. The assignments are facilitated by agreement between observed and calculated isotopic patterns and MSn studies. Single-crystal X-ray crystallography of (Bu3Sn[O2CC6H4{NN(C6H3-4-OH(C(H)NC6H4OCH3-4))}-o])n reveals a polymeric structure. Toxicity studies of the tributyltin(IV) complexes of the 4-[((E)-1-{2-hydroxy-5-[(E)-2-(2-carboxyphenyl)-1-diazenyl]phenyl}methylidene)amino]aryls on the second larval instar of the Aedes aegypti and Anopheles stephensi mosquito larvae are also reported. The LC50 values indicate that the complexes are effective larvicides, which range from a low of 0.36 ppm to a high of 0.69 ppm against the Ae. aegypti larvae and between 0.82 and 1.17 ppm against the An. stephensi larvae. Copyright © 2005 John Wiley & Sons, Ltd.