Highly Active and Diastereoselective <i>N,O</i>‐ and <i>N,N</i>‐Yttrium Complexes for Intramolecular Hydroamination

Abstract

Abstract The intramolecular hydroamination of aminoalkynes and unactivated aminoalkenes catalyzed by yttrium N,O ‐ and N,N ‐complexes has been investigated. The N,N ‐yttrium complexes are highly active, catalyzing the conversion of a wide range of terminal aminoalkenes at room temperature, and internal aminoalkenes at elevated temperature, to yield pyrrolidine and piperidine products in high yields. A high diastereoselectivity of up to 23:1 is observed at 0 °C with 1‐methyl‐4‐pentenylamine as substrate.