Rhodium‐Catalyzed Asymmetric Hydroformylation of <i>N</i>‐Allylamides: Highly Enantioselective Approach to β²‐Amino Aldehydes

Abstract

You′re having a lahf! The asymmetric hydroformylation (AHF) of allylic compounds, catalyzed by a rhodium–yanphos complex, is a direct and concise route to β2-amino aldehydes, acids, and alcohols with excellent enantioselectivity (see scheme; TON=turnover number, acac=acetylacetonate). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.