Basic, not acidic fibroblast growth factor stimulates proliferation of cultured human retinal pigment epithelial cells.

Abstract

bFGF, in contrast to its analogue aFGF, stimulates cell proliferation in cultured human RPE cells. It may act as an autocrinic agent (secretion by and action on the same cell) and thus be a specific regulator for cell proliferation in repair and replacement of the RPE cell monolayer.