Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice

Induction of Sonic Hedgehog Mediators by Transforming Growth Factor-β: Smad3-Dependent Activation of <i>Gli2</i> and <i>Gli1</i> Expression <i>In vitro</i> and <i>In vivo</i>

Sylviane Dennler, Jocelyne André, Vasileia Ismini Alexaki et al. · Cancer Research · 2007 · 345 citations · Full text

Life Sciences, Cell Biology, Oncology +13

TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

Kristian P. Doyle, Egle Cekanaviciute, Lauren Mamer et al. · Journal of Neuroinflammation · 2010 · 259 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

Liu Yang, Ying Wang, Hua Mao et al. · Journal of Hepatology · 2007 · 200 citations · Full text

Life Sciences, Cell Biology, Genetics +14

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

Rafal P. Witek, Liu Yang, Renshui Liu et al. · Gastroenterology · 2008 · 200 citations

Life Sciences, Biochemistry, Cell Biology +12

Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation

Dolores Hambardzumyan, Stephanie M. Pyonteck, Oren J. Becher et al. · Journal of Neuroscience · 2009 · 199 citations · Full text

Medicine, Neurobiology, Neuroscience +14