Identification of Cucumisin (Cuc m 1), a subtilisin‐like endopeptidase, as the major allergen of melon fruit

Abstract

Cucumisin (Cuc m 1) and several N-terminal cucumisin fragments are the major allergens of melon. The ubiquitous distribution of this protein family (cucumisin-like proteases) in many plant species and its high structural similarity suggest its potential role as a new panallergen in plant foods.