Advanced Materials · 2012 · 966 citations · 32 references
PharmacyOncologyPharmacologyDrug DeliveryNanoparticle Drug DeliveryTheranosticsCancer NanomedicineCancer TheranosticsNanocarriers For TherapeuticsNanomedicineNanoparticle Delivery SystemsTheranostic NanoparticlesCancer NanotherapyIntracellular Drug LocalizationTheranostic AgentsTheranostic NanomaterialsTheranostic NanomedicineTheranostic PlatformsTwo-photon Fluorescence ImagingTwo-photon Microscopy
Mesoporous silica-coated gold nanorods ([email protected]2) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of [email protected]2 is visualized through two-photon imaging. With doxorubicin hydrochloride loaded, [email protected]2–DOX show two light-mediated therapeutic modes: low power density laser-triggered drug release for chemotherapy, and high power density laser-induced hyperthermia, which suggest the potential for in-vivo applications. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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