POLYMORPHISMS OF N-ACETYLTRANSFERASE 2, GLUTATHIONE S-TRANSFERASE MU AND THETA GENES AS RISK FACTORS OF BLADDER CANCER IN RELATION TO ASTHMA AND TUBERCULOSIS

Abstract

Among Korean subjects, GSTM1 null genotype was a significant risk factor for bladder cancer. The reason why bronchial asthma and tuberculosis are risk factors in Korean subjects is yet unknown, but a variety of factors, including enzyme activities for detoxification, medication for these diseases and immunological background might be involved.