Hemodynamic Activation of β-Catenin and T-Cell-Specific Transcription Factor Signaling in Vascular Endothelium Regulates Fibronectin Expression - Concepedia

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Hemodynamic Activation of β-Catenin and T-Cell-Specific Transcription Factor Signaling in Vascular Endothelium Regulates Fibronectin Expression

DOI Full Paper Access

66

Citations

53

References

2011

Year

Bradley D. Gelfand, Julia Meller, Andrew Pryor, Michaël Kahn, Pamela D. Schoppee Bortz, Brian R. Wamhoff, Brett R. Blackman

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

These data reveal novel constitutive activation of the endothelial β-catenin/TCF signaling pathway in atherosclerosis and regulation of fibronectin through hemodynamic shear stress.

References

	Year	Citations
Hemodynamic Shear Stress and Its Role in Atherosclerosis Adel M. Malek JAMA HypertensionVascular DiseaseEngineeringPathologyArterial-level Shear Stress	1999	3.5K
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions Robert E. Gerszten, Eduardo A. García‐Zepeda, Yaw-Chyn Lim, Nature Endothelial Cell PathobiologyInflammationCytokineAngiogenesisCell Adhesion	1999	1.2K
A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription Katayoon H. Emami, Cu Nguyen, Hong Ma, Proceedings of the National Academy of Sciences	2004	857
Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation Lilia Topol, Xueyuan Jiang, Hosoon Choi, The Journal of Cell Biology Canonical Wnt PathwayGsk-3–independent β-Catenin DegradationSystems BiologySignal TransductionDevelopmental Biology	2003	718
Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature Guohao Dai, Mohammad R. K. Mofrad, Sripriya Natarajan, Proceedings of the National Academy of Sciences Vascular DiseaseEngineeringCarotid Artery BifurcationsBiomedical EngineeringBlood Flow	2004	662
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates Andreas Hecht The EMBO Journal Transcriptional RegulationSignal TransductionDevelopmental BiologySignaling PathwayMolecular Regulation	2000	606
Biomechanical activation of vascular endothelium as a determinant of its functional phenotype Guillermo García‐Cardeña, Jason Comander, Keith R. Anderson, Proceedings of the National Academy of Sciences	2001	525
Wnt Signaling Mediates Self-Organization and Axis Formation in Embryoid Bodies Derk ten Berge, Wouter Koole, Christophe Fuerer, Cell stem cell Developmental BiologyAxis FormationMorphogenesisEmbryonic DevelopmentCell Fate Determination	2008	478
Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling Ximei Wu, Xiaolin Tu, Kyu Sang Joeng, Cell Transcriptional RegulationSystems BiologySignal TransductionSignaling PathwayCell Regulation	2008	472
The Transcriptional Coactivator Cbp Interacts with β-Catenin to Activate Gene Expression Ken‐Ichi Takemaru, Randall T. Moon The Journal of Cell Biology	2000	468

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