Circulation Research · 1957 · 36 citations · 7 references
Life SciencesCardiologyPhysiologyClinical CardiologyAltitude PhysiologyCardiac PhysiologyCardiovascular DiseaseCardiovascular PhysiologyHemodynamicsPulmonary HypertensionCardiovascular Responses To AltitudeEtiologic HypothesisHigh-altitude PhysiologyHyperbaric ExposureHypertension PathophysiologyPulmonary Hypertension At AltitudeRight Heart HemodynamicsRight Ventricular Hemodynamics
Guinea pigs exposed to simulated altitudes of 18,000 feet developed right heart dilatation followed by hypertrophy, more conspicuous in the infundibular area of the right ventricle. Under the described experimental conditions, pulmonary artery hypertension may be the etiologic factor.
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