The use of¹³C–{¹H selective} nuclear Overhauser enhancement experiments in the determination of the structure of a highly crowded quinone–diazoalkane epoxide adduct

Abstract

Using heteronuclear nuclear Overhauser enhancement techniques the structure and conformation have been established for a highly crowded quinone–diazoalkane epoxide adduct, (3aS*,9S*,9aR*)-3,9a-dihydro-3,3,3′,3′,9a-pentamethylspiro-[9H-benz[f] indazole-9,2′-oxiran]-4(3aH)-one, formed from 2-methylnaphthoquinone and 2-diazopropane.