Concepedia

Fluorescent Color Readout of DNA Hybridization with Thiazole Orange as an Artificial DNA Base

Sina Berndl, Hans‐Achim Wagenknecht

Angewandte Chemie International Edition · 2009 · 92 citations · 48 references

DOI

Concepts

Abstract

A fluorescent chameleon: A single thiazole orange (TO) dye, when used as an artificial DNA base shows the typical green emission, whereas the interstrand TO dimer exhibits an orange excimer-type emission inside duplex DNA (see picture).

References

48

Molecular Beacons: Probes that Fluoresce upon Hybridization

Sanjay Tyagi, Fred Russell Kramer · Nature Biotechnology · 1996 · 4.2K citations

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Stable fluorescent complexes of double-stranded DNA with bis-intercalating asymmetric cyanine dyes: properties and applications

Hays S. Rye, Stephen Yue, David E. Wemmer et al. · Nucleic Acids Research · 1992 · 671 citations · Full text

, , +17

The Dimeric State of Cyanine Dyes

William West, Sandra Pearce · The Journal of Physical Chemistry · 1965 · 534 citations

, , +5

Wavelength-shifting molecular beacons

Sanjay Tyagi, Salvatore A. E. Marras, Fred Russell Kramer · Nature Biotechnology · 2000 · 337 citations

Pyrene Excimer Signaling Molecular Beacons for Probing Nucleic Acids

Patrick R. Conlon, Chaoyong Yang, Yanrong Wu et al. · Journal of the American Chemical Society · 2007 · 307 citations · Full text

, , +14