Transport of Cisplatin by the Copper Efflux Transporter ATP7B

Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells

Roohangiz Safaei, Barrett J. Larson, Timothy Cheng et al. · Molecular Cancer Therapeutics · 2005 · 552 citations

Life Sciences, Cell Biology, Oncology +17

CPx-type ATPases: a class of P-type ATPases that pump heavy metals

Marc Solioz, Chris D. Vulpe · Trends in Biochemical Sciences · 1996 · 477 citations

Life Sciences, Biochemistry, Biophysics +4

Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance.

Masanobu Komatsu, Tomoyuki Sumizawa, Masato Mutoh et al. · PubMed · 2000 · 333 citations

Medicine, Cancer Biology, Oncology +15

Biochemical Characterization of the Wilson Disease Protein and Functional Expression in the Yeast Saccharomyces cerevisiae

Irene H. Hung, Mariko Suzuki, Yukitoshi Yamaguchi et al. · Journal of Biological Chemistry · 1997 · 327 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper.

Kuniyuki Katano, Akira Kondo, Roohangiz Safaei et al. · PubMed · 2002 · 294 citations

Medicine, Oncology, Pharmacology +15