Comparison of Bariatric Surgical Procedures for Diabetes Remission: Efficacy and Mechanisms

Abstract

In Brief Bariatric surgery induces a mean weight loss of 15–30% of initial body weight (depending on the procedure), as well as a 45–95% rate of diabetes remission. Procedures that induce greater weight loss are associated with higher rates of diabetes remission. Improvements in glucose homeostasis after bariatric surgery are likely mediated by a combination of caloric restriction (followed by weight loss) and the effects of altered gut anatomy on the secretion of glucoregulatory gut hormones.