Radiation Research · 1998 · 115 citations · 16 references
Alternating Gradient SynchrotronEngineeringRadiation ExposureSynchrotron Radiation SourceDetailed CharacterizationSynchrotron Radiation ResearchMev/nucleon Iron BeamInstrumentationRadiation OncologyNuclear MedicineBiophysicsDepth-dose DistributionRadiation DetectionPhysicsMev/nucleon BeamSynchrotron RadiationDosimetryMev/nucleon Iron-56 BeamApplied PhysicsRadiation DoseMedicine
We report beam characterization and dosimetric measurements made using a 56Fe beam extracted from the Brookhaven National Laboratory Alternating Gradient Synchrotron (AGS) with a kinetic energy of 1087 MeV/nucleon. The measurements reveal that the depth-dose distribution of this beam differs significantly from that obtained with a 600 MeV/nucleon iron beam used in several earlier radiobiology experiments at the Lawrence Berkeley National Laboratory's BEVALAC. We present detailed measurements of beam parameters relevant for radiobiology, including track- and dose-averaged linear energy transfer (LET), fragment composition and LET spectra measured behind sample holders used in irradiations of biological samples. We also report measurements of fluence behind three depths (1.94, 4.68 and 9.35 g cm(-2)) of polyethylene targets with the 1087 MeV/nucleon beam, and behind 1.94 g cm(-2) of polyethylene with a 610 MeV/nucleon beam delivered by the AGS. These results are compared to earlier measurements with the 600 MeV/nucleon beam at the BEVALAC.
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