Characterization of the Soluble Form of the Low Density Lipoprotein Receptor-Related Protein (LRP)

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

Life Sciences, Cell Biology, Immunology +14

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed · 1988 · 2.4K citations

Medicine, Oncology, Pharmacology +9

An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon, Jennifer L. Slack, P. Linga Reddy et al. · Science · 1998 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +10

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

Dudley K. Strickland, James Ashcom, Suzanne E. Williams et al. · Journal of Biological Chemistry · 1990 · 660 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

Kendall M. Mohler, Paul R. Sleath, Jeffrey N. Fitzner et al. · Nature · 1994 · 600 citations

Veterinary Medicine, Immunology, Pharmacology +11