Nitrobenzylation of α-carbonyl ester derivatives using TDAE approach

Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study.

Douglas L. Fraker, H. Richard Alexander, Mary P. Andrich et al. · Journal of Clinical Oncology · 1996 · 212 citations

Medicine, Oncology, Pharmacotherapy +17

Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver.

H. Richard Alexander, David L. Bartlett, Steven K. Libutti et al. · Journal of Clinical Oncology · 1998 · 183 citations

Medicine, Oncology, Surgery +14

Disposition and Tumor Localization of Mitomycin C–Dextran Conjugates in Mice

Yoshinobu Takakura, Akira Takagi, Mitsuru Hashida et al. · Pharmaceutical Research · 1987 · 177 citations

Pharmacy, Oncology, Pharmacokinetics +13

Cyto-active amino-acid and peptide derivatives. Part I. Substituted phenylalanines

F. Bergel, J. A. Stock · Journal of the Chemical Society (Resumed) · 1954 · 163 citations

Natural Sciences, Biochemistry, Organic Chemistry +6

Tetrakis(dimethylamino)ethylene as a Useful Reductant of Some Bromodifluoromethyl Heterocycles. Application to the Synthesis of New <i>gem</i>-Difluorinated Heteroarylated Compounds

Conrad R. Burkholder, William R. Dolbier, Maurice Médebielle · The Journal of Organic Chemistry · 1998 · 108 citations

Natural Sciences, Chemistry, Organic Chemistry +7