Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects - Concepedia

Concepedia

Publication | Open Access

Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects

DOI Full Paper Access

75

Citations

30

References

2014

Year

Ji Young Yoo, Brian Hurwitz, Chelsea Bolyard, Jun-Ge Yu, Jianying Zhang, Karuppaiyah Selvendiran, Kellie S. Rath, Shun He, Zachary S. Bailey, David Eaves,

Clinical Cancer Research

Abstract

The dramatic synergy of bortezomib and 34.5ENVE is mediated by bortezomib-induced UPR and warrants future clinical testing in patients.

References

	Year	Citations

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