Genetics Research · 1961 · 28 citations · 4 references
Life SciencesBiostatisticsGeneticsPopulation GeneticsQuantitative GeneticsStatistical GeneticsGenetic CorrelationGenotype-phenotype Association AnalysisGenotype-phenotype CorrelationHeritabilityPolygenic TraitsQuantitative Trait AnalysisCorrelated Response To SelectionFamily-based HeritabilityGenetic Correlation AnalysisGenetic Heritability EstimationHeritability Of Quantitative TraitsPedigree-based HeritabilityQuantitative Trait HeritabilitySelection Response Estimation
A method for obtaining linear estimates of heritability and genetic correlation is given. It is based, essentially, on selecting, from a pedigreed population, prospective parents for which estimates of average genotype and phenotype values are obtained; a regression of genotype on phenotype value is then determined from a straight line fitted through points representing the population mean genotype and phenotype on one hand and the mean genotype and phenotype of selected parents on the other. The method permits an evaluation of asymmetry in response for a trait selected in both directions, as well as asymmetry in correlated response to selection of two different traits, with data from a single pedigreed population.
4
The genetics of litter size in mice
D. S. Falconer · Journal of Cellular and Comparative Physiology · 1960 · 159 citations
Life Sciences, Biology, Genetics +7
Selection of mice for growth on high and low planes of nutrition
D. S. Falconer · Genetics Research · 1960 · 157 citations · Full text
Life Sciences, Biology, Genetics +17