Detection of Increased ⁶⁴Cu Uptake by Human Copper Transporter 1 Gene Overexpression Using PET with ⁶⁴CuCl₂ in Human Breast Cancer Xenograft Model

Abstract

An increase in (64)Cu uptake induced by the expression of hCTR1 gene was demonstrated in vivo and in vitro, suggesting the potential use of hCTR1 gene as a new imaging reporter gene for PET with (64)CuCl2.