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The Cell Site of the Immunological Defect in Tumor-Bearing Mice
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1971
Year
ImmunologyBlood CellPathologyImmunologic MechanismReactive SplenomegalySpleen CellsImmunotherapyHematologyTumor ImmunityLymphatic SystemAutoimmune DiseaseGranulocyteAutoimmunityCell BiologyTumor MicroenvironmentCancer ImmunosurveillanceMedicineTumor-bearing MiceCell Site
In vivo studies have shown that in spite of the reactive splenomegaly with lymphoid cell hyperplasia, which is a constant finding in tumor-bearing mice, the capacity of the spleen cells to respond to injected SRBC by hemolysin production is significantly impaired.