Altered levels of miR‐21, miR‐125b‐2*, miR‐138, miR‐155, miR‐184, and miR‐205 in oral squamous cell carcinoma and association with clinicopathological characteristics

Abstract

Our results corroborate the previous findings on the overexpression of mir-21 and downregulation of miR-138 in OSCC. As the expression of miR-184 is controversial in tongue/oral cancer, the downregulation may be specific to tumor anatomical localization. On the other hand, to the best of our knowledge, this is the first report to show the association of miR-155 with tobacco chewing and the downregulation of miR-125b-2* in OSCC. Computational predictions suggest that miR-125b-2* may have a role in alternative splicing.