mBAND analysis of chromosome aberrations in lymphocytes exposed<i>in vitro</i>to α-particles and γ-rays

Abstract

This study has confirmed that exchanges induced by exposure to high linear energy transfer (LET) alpha-particle radiation comprise a greater proportion of intrachanges than those induced by exposure to low LET gamma-rays. However, since the majority of these are associated with complex rearrangements and likely to be non-transmissible, this limits their applicability as a marker of past in vivo exposure.