Enantioselective synthesis of (R)- or (S)-2-alkylglutaraldehydic acid methyl esters via chiral organotin enamines - Concepedia

Concepedia

Publication | Closed Access

Enantioselective synthesis of (R)- or (S)-2-alkylglutaraldehydic acid methyl esters via chiral organotin enamines

14

Citations

0

References

1985

Year

Brigitte Nebout, B. DE JESO, Jean-Claude Pommier

Journal of the Chemical Society Chemical Communications

EngineeringNucleophilic AdditionChiral Organotin EnaminesOrganic ChemistryAcid Methyl EstersChemistryStereoselective SynthesisPharmacologyAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringElectrophilic Alkenes

Abstract

Nucleophilic addition of chiral organotin enamines to electrophilic alkenes is described; a minor modification of experimental conditions gave the other enantiomer of 2-alkylglutaraldehydic acid methyl esters.