Dermatologic Surgery · 1996 · 154 citations · 14 references
MedicineDermatologySurgeryBiomedical OpticsBiophotonicsVascular SurgeryBiomedical Laser ApplicationsLaser SurgeryPhotothermal TherapyVascular Lesion TreatmentCutaneous Blood VesselsLaser Therapy Of Vascular LesionsMulticenter TrialsPhotothermal EffectsPulsed Dye Laser TherapyPulsed Light TreatmentSelectivity Of Photothermolysis
BACKGROUND: The flashlamp-pumped pulse dye laser at 585 nm has previously been reported to be somewhat effective in treating leg telangiectasia with diameters less than 0.2 mm. A pulsed photothermal devise (intense pulsed light source [IPLS]) has been developed to treat leg veins ranging in size from 0.1 to 3 mm in diameter. Vessel necrosis occurs from an intense pulsed light that penetrates through the skin and is absorbed by the blood vessels based on the principle of selective photothermolysis. OBJECTIVE: To determine the effectiveness of this novel device on treating leg veins. METHODS: One hundred fifty-nine patients with 369 lesions were treated with the IPLS in a multicenter trial. RESULTS: Clearance of 75-100% was achieved in 79% of treated lesions. Better than 50% clearance was achieved in 94% of completed cases. A very low rate of adverse effects occurred. CONCLUSION: The IPLS is a safe and effective modality to treat leg veins ranging in size from 0.1 to 3 mm in diameter.
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Diffusion of light in turbid material
Akira Ishimaru · Applied Optics · 1989 · 325 citations
The Treatment of Port-wine Stains by the Pulsed Dye Laser
Jerome M. Garden · Archives of Dermatology · 1988 · 270 citations
Medicine, Dermatology, Biophotonics +12
Tunable Pulsed Dye Laser for the Treatment of Benign Cutaneous Vascular Ectasia
Luigi L. Polla, Oon Tian Tan, Jerome M. Garden et al. · Dermatologica · 2009 · 144 citations
Medicine, Dermatology, Surgery +17