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Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human γδ T cells but does not lead to competitive antagonism

Pyrophosphate GroupCompetitive AntagonismSignal TransductionNatural SciencesImmunologyMolecular BiologyImmunologic MechanismDiphosphonate FunctionCellular BiochemistryCellular Immune ResponseMedicineCell BiologyCell SignalingCellular PhysiologyProtein Phosphorylation